NCT06501391View on ClinicalTrials.gov

Cranial Radiotherapy Plus Chemoimmunotherapy in Untreated Driver-mutation Negative NSCLC With Stable Brain Metastasis

PHASE2RecruitingINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

July 1, 2024

Primary Completion Date

July 31, 2026

Study Completion Date

July 31, 2027

Conditions
NSCLC Stage IVBrain Metastases
Interventions
DRUG

PD-L1/PD-1 inhibitor and chemotherapy

Stable brain metastases patients in this arm will receive PD-L1/PD-1 inhibitors and chemotherapy.

RADIATION

SRT or WBRT

Stable brain metastases (BM) patients in this arm will receive stereotactic radiotherapy (SRT) and whole brain radiation therapy (WBRT) according to their BM condition.

Trial Locations (1)

Unknown

RECRUITING

Fudan University Shanghai Cancer Center, Shanghai

All Listed Sponsors
lead

Fudan University

OTHER