Safety and Pharmacokinetics Study of MBX 2109 in Adult Subjects With Normal and Impaired Renal Function

PHASE1RecruitingINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

May 24, 2024

Primary Completion Date

October 12, 2024

Study Completion Date

October 12, 2024

Conditions
Renal Impairment
Interventions
DRUG

MBX 2109

Group 1: Subjects with mild renal impairment (eGFR ≥ 60 and \< 90 mL/min)

DRUG

MBX 2109

Group 2: Subjects with moderate renal impairment (eGFR ≥ 30 and \< 60 mL/min)

DRUG

MBX 2109

Group 3: Subjects with severe renal impairment (eGFR \< 30 mL/min), or kidney failure and not receiving dialysis

DRUG

MBX 2109

Group 4: Matched healthy subjects with normal renal function (eGFR ≥ 90 mL/min)

Trial Locations (3)

33136

RECRUITING

MBX Biosciences Investigational Site, Miami

33603

RECRUITING

MBX Bioscience Investigational Site, Tampa

55101

RECRUITING

MBX Biosciences Investigational Site, Minneapolis

Sponsors

Lead Sponsor

All Listed Sponsors
lead

MBX Biosciences

INDUSTRY

NCT06496217 - Safety and Pharmacokinetics Study of MBX 2109 in Adult Subjects With Normal and Impaired Renal Function | Biotech Hunter | Biotech Hunter