400
Participants
Start Date
October 1, 2025
Primary Completion Date
April 1, 2027
Study Completion Date
April 1, 2027
colistimethate sodium
100 000 IU/kg of colistimethate sodium (equivalent to 0.96 mg/kg of colistin base) ,maximum 750000 IU, will be nebulized daily, divided into two doses for a maximum of 7 days for eligible ventilated children starting from day 3 of mechanical ventilation.
0.9% Saline
Nebulization of 3 ml of 0.9% saline twice a day for a maximum of 7 days from day 3 of invasive mechanical ventilation for eligibile ventilated children
University Hospital Fattouma Bourguiba
OTHER