TACE Plus Camrelizumab and Apatinib for Unresectable Hepatocellular Carcinoma

PHASE3RecruitingINTERVENTIONAL
Enrollment

101

Participants

Timeline

Start Date

July 1, 2024

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2028

Conditions
Unresectable Hepatocellular CarcinomaTransarterial ChemoembolizationCamrelizumabApatinib
Interventions
COMBINATION_PRODUCT

TACE plus camrelizumab and apatinib

"TACE plus camrelizumab and apatinib group:~Patients who were randomized to this group, TACE is performed via an injection into the hepatic artery of agents by puncturing the common femoral artery.Adriamycin(30 to 60 mg) and oxaliplatin (50-150mg) are considered as basic chemotherapy drugs in the process of transcatheter endovascular perfusion. The dose of lipiodol (5-20ml) and other embolic agent( blank microspheres/ PVA/gelatin sponge particles) were determined by diameter and blood supply type of HCC. Within 1 week after first TACE treatment, camrelizumab 200mg intravenously every 3 weeks and apatinib 250 mg orally once daily."

COMBINATION_PRODUCT

Camrelizumab and apatinib

"Camrelizumab and apatinib group:~Patients who were randomized to this group, camrelizumab 200mg intravenously every 3 weeks and apatinib 250 mg orally once daily."

Trial Locations (1)

610041

RECRUITING

Sichuan Cancer Hospital and Research Institute, Chengdu

All Listed Sponsors
lead

Guohui Xu

OTHER