584
Participants
Start Date
November 30, 2024
Primary Completion Date
December 31, 2033
Study Completion Date
December 31, 2033
High-intensity radiological surveillance
The standard approach to surveillance imaging will be contrasted CT (IV and oral contrast) of the chest, abdomen and pelvis. All patients require radiological assessment of the chest, abdomen and pelvis at each surveillance round. Tolerance will be given in the protocol for selected patients where CT is not suitable to receive alternative imaging such as MRI or combination of MRI and CT. Uncontrasted CT imaging is permissible where renal toxicity or allergy from intravenous contrast is of concern. The use of plain radiography is not permitted as an alternative to CT imaging of the chest.
Lower-intensity radiological surveillance
The standard approach to surveillance imaging will be contrasted CT (IV and oral contrast) of the chest, abdomen and pelvis. All patients require radiological assessment of the chest, abdomen and pelvis at each surveillance round. Tolerance will be given in the protocol for selected patients where CT is not suitable to receive alternative imaging such as MRI or combination of MRI and CT. Uncontrasted CT imaging is permissible where renal toxicity or allergy from intravenous contrast is of concern. The use of plain radiography is not permitted as an alternative to CT imaging of the chest.
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
University Hospitals Birmingham NHS Foundation Trust, Birmingham
Collaborators (2)
University of Birmingham
OTHER
University Hospital Birmingham NHS Foundation Trust
OTHER
Royal Marsden NHS Foundation Trust
OTHER
University Hospital Padova
OTHER
Campus Bio-Medico University
OTHER
The Netherlands Cancer Institute
OTHER
KU Leuven
OTHER
Heidelberg University
OTHER
Dana-Farber/Brigham and Women's Cancer Center
OTHER
Emory University
OTHER
Mayo Clinic
OTHER
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
OTHER
The Cleveland Clinic
OTHER
M.D. Anderson Cancer Center
OTHER
University of Southern California
OTHER
Ohio State University
OTHER
Ottawa Hospital Research Institute
OTHER
McGill University
OTHER
Peter MacCallum Cancer Centre, Australia
OTHER
Royal Prince Alfred Hospital, Sydney, Australia
OTHER
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
OTHER