A Study of Adebrelimab Combined With Chemoradiotherapy in the Treatment of Esophageal Small Cell Carcinoma

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

July 13, 2024

Primary Completion Date

July 13, 2026

Study Completion Date

July 13, 2027

Conditions
Esophageal Small Cell Carcinoma
Interventions
DRUG

Etoposide

100mg/m\^2, intravenous infusion for 1-3 days,21 days/cycle, 4 cycles

DRUG

Cisplatin

25mg/m\^2 ,intravenous infusion for 1-3 days ,21 days/cycle, 4 cycles

DRUG

Carboplatin

Carboplatin (AUC = 5) on 1 Day,21 days/cycle, 4 cycles ;

DRUG

Adebrelimab

1200mg adebrelimab was given intravenously on 2 day after chemotherapy,21 days/cycle, continuous use.

RADIATION

radiotherapy

Stage I-IVa , prescription dose: PTV 50Gy/25f. Stage IVb ,prescribed dose: PTV 30Gy/10f.

All Listed Sponsors
lead

Zhangzhou Municipal Hospital

OTHER