Evaluate the Safety and Efficacy of BGT007H Cell Therapy in Patients With Relapsed/Refractory Pancreatic Cancer

NARecruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

May 7, 2024

Primary Completion Date

March 31, 2027

Study Completion Date

August 31, 2027

Conditions
Tumor Pancreas
Interventions
DRUG

BGT007H Cell Injection

"Intervention roughly goes through 3 phases (the day of cell infusion is defined as day 0, d0):~1. Apheresis and baseline period: Eligible subjects are enrolled for leukapheresis to prepare BGT007H cell injection solution, and baseline assessment is performed from after apheresis to before preconditioning.~2. Preconditioning (d-5\~d-3): Patients begin preconditioning (FC regimen) 5 days before BGT007H cell administration. A 2-day rest and observation period is conducted after preconditioning.~ The FC regimen is as follows:~ * Fludarabine: 25\~30mg/m2/d, intravenous infusion, once a day, for 3 consecutive days;~ * Cyclophosphamide: 250\~350mg/m2/d, intravenous infusion, once a day, for 3 consecutive days.~3. Cell infusion (d0) and DLT observation period (d0\~d28)."

Trial Locations (1)

200127

RECRUITING

Renji hospital, Shanghai

All Listed Sponsors
lead

RenJi Hospital

OTHER