NCT06478017 - Belatacept in Heart Transplantation | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 29, 2025

Primary Completion Date

January 31, 2028

Study Completion Date

January 31, 2028

Conditions

Heart Transplant

Interventions

DRUG

Belatacept

"Patients will receive 10mg/kg on Day 3 post-transplant (72 hours +/- 12 hours post-transplant)~Day 7 post-transplant (+/- 6 hours)~Day 16 (End of Week 2 after 1st dose of belatacept) post-transplant (+/- 2 days)~Day 30 (End of Week 4 after 1st dose of belatacept) post-transplant (+/- 3 days)~Day 58 (Week 8) post-transplant (+/- 3 days)~Day 86 (Week 12) post-transplant (+/- 3 days)~Patients will receive 5mg/kg Every 28 days (+/- 3 days) thereafter"

DRUG

Tacrolimus

Prograf (tacrolimus) or tacrolimus generic

DRUG

Mycophenolate Mofetil/Sodium

CellCept (mycophenolate mofetil- MMF), or Myfortic (mycophenolate sodium)

DRUG

Prednisone

Trial Locations (4)

10016

RECRUITING

NYU Langone Health (Site # 71177), New York

33606

RECRUITING

Tampa General Hospital (Site # 71150), Tampa

84132

RECRUITING

University of Utah Medical Center (Site # 71126), Salt Lake City

90048

RECRUITING

Cedars Sinai Heart Institute/ Cedars Sinai Medical (Site # 71146), Los Angeles

All Listed Sponsors

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH