Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy

PHASE2RecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

November 14, 2024

Primary Completion Date

July 1, 2028

Study Completion Date

July 1, 2028

Conditions
Head and Neck Cancer
Interventions
DRUG

ENI using IMRT with or without chemotherapy

This study is a phase II single-blinded randomized trial comparing standard ENI with involved nodal radiotherapy. INRT using intensity modulated radiation therapy (IMRT) with or without chemotherapy (if given, either cisplatin, cetuximab, or carboplatin- paclitaxel)

RADIATION

INRT

INRT using intensity modulated radiation therapy (IMRT) with or without chemotherapy (if given, either cisplatin, cetuximab, or carboplatin- paclitaxel)

RADIATION

ENI

ENI using IMRT with or without chemotherapy

Trial Locations (1)

75390

RECRUITING

UT Southwestern Medical Center, Dallas

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

University of Texas Southwestern Medical Center

OTHER