Adebrelimab + Apatinib in SCLC Maintenance Therapy

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 20, 2024

Primary Completion Date

December 20, 2025

Study Completion Date

December 20, 2026

Conditions
SCLC
Interventions
DRUG

Adebrelimab combined with Apatinib

Each treatment cycle spans 3 weeks. Sequential medication administration begins on the first day of each cycle: Atezolizumab is administered at a dosage of 1200mg on day 1, every 3 weeks, while Apatinib is given orally at a dosage of 250mg daily from day 1 to day 14, every 3 weeks, with a one-week hiatus following two weeks of continuous intake. Administration timing allows for a window of ±5 days. Subjects are required to undergo comprehensive assessments, including vital signs monitoring, anthropometric measurements, physical examinations, laboratory analyses, and performance status evaluations, to assess treatment tolerability for continuation.

Trial Locations (1)

710038

RECRUITING

Tangdu Hospital Affiliated to the Fourth Military Medical University, Xi'an

All Listed Sponsors
collaborator

Jiangsu Hengrui Pharmaceutical Co., Ltd.

INDUSTRY

lead

Tang-Du Hospital

OTHER