1,300
Participants
Start Date
December 23, 2024
Primary Completion Date
December 8, 2027
Study Completion Date
December 8, 2028
Prednisolone 30 mg
This is a glucocorticoid like cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic and vasoconstrictive effects. It binds to the glucocorticoid receptor, inhibiting pro-inflammatory signals and promoting anti-inflammatory signals. It has a short duration of action as the half-life is 2.1-3.5 hours and 98% is eliminated in urine. On 21 June 1955 it was granted FDA approval.
Placebo
This a tablet identical to prednisolone.
RECRUITING
Queen Mary Hospital, Hong Kong
The University of Hong Kong
OTHER