Renal Outcomes in the Early Use of Vasopressin in the Treatment of Septic Shock

PHASE4RecruitingINTERVENTIONAL
Enrollment

264

Participants

Timeline

Start Date

May 15, 2024

Primary Completion Date

May 15, 2026

Study Completion Date

May 15, 2026

Conditions
Septic ShockRenal Function Replacement
Interventions
DRUG

vasopressin infusion when the norepinephrine dosage is equal to or greater than 0.25 mcg/kg/min

when the norepinephrine dosage is equal to or greater than 0.25 mcg/kg/min in the absence of adequate MAP (Mean arterial pressure \>65 mmhg), vasopressin infusion will be associated with the standard dosage of 0.3UI/min.

DRUG

vasopressin infusion when the norepinephrine dosage is equal to or greater than 0.5 mcg/kg/min

the infusion of vasopressin at a dosage of 0.3 IU/min will be associated if norepinephrine exceeds the dosage of 0.5 mcg/kg/min in the absence of adequate MAP

Trial Locations (1)

40100

RECRUITING

Azienda Unità Sanitaria Locale, Bologna

All Listed Sponsors
lead

Azienda Usl di Bologna

OTHER_GOV