A Study to Evaluate the MNV-201 in Patients With Low Risk MDS

PHASE1RecruitingINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

May 27, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2029

Conditions
Myelodysplastic Syndromes
Interventions
BIOLOGICAL

MNV-201 (Autologous CD34+ Cells Enriched with allogenic Placenta Derived Mitochondria)

"The participant will undergo 5 days of mobilization by G-CSF administration (Neupogen) once a day during 5 days.~On the 5th day, and after receiving the last dose of Neupogen, the participant will undergo Apheresis to collect CD34+ cells.~MNV-201 consists of autologous CD34+ cells enriched with allogeneic placenta derived mitochondria. Autologous CD34+ cells are isolated from the participant's peripheral blood after mobilization by apheresis. Allogeneic mitochondria are isolated under aseptic conditions from healthy donor placenta, cryopreserved and qualified before use.~Each product package will consist of a ready-for-injection sterile infusion bag containing clinical grade MNV-201 product for IV infusion for a single specified (autologous) participant."

Trial Locations (1)

9103102

RECRUITING

Shaare Zedek Medical Center, Jerusalem

Sponsors
All Listed Sponsors
lead

Minovia Therapeutics Ltd.

INDUSTRY

NCT06465160 - A Study to Evaluate the MNV-201 in Patients With Low Risk MDS | Biotech Hunter | Biotech Hunter