A Real-World Study of Neoadjuvant/Conversion Therapy for Locally Advanced or Metastatic Gastric Cancer

Not yet recruitingOBSERVATIONAL
Enrollment

70

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2027

Conditions
Gastric Cancer
Interventions
COMBINATION_PRODUCT

fruquintinib combined with immune checkpoint inhibitors and chemotherapy

"Chemotherapy Drugs: Selection based on clinical guidelines/indications and patient condition.For example, recommended chemotherapy regimens: XELOX or SOX.~Immune Checkpoint Inhibitors:~Selection based on clinical guidelines/indications and patient condition, including but not limited to PD-1 inhibitors, PD-L1 inhibitors.~Fruquintinib: 3mg (starting dose), PO (once daily). Dosing schedule and dosage can be adjusted based on concurrent chemotherapy and immune checkpoint inhibitors. Have received fruquintinib treatment for at least 2 cycles."

COMBINATION_PRODUCT

fruquintinib combined with immune checkpoint inhibitors and chemotherapy

"Chemotherapy Drugs: Selection based on clinical guidelines/indications and patient condition.For example, recommended chemotherapy regimens: XELOX or SOX.~Immune Checkpoint Inhibitors:~Selection based on clinical guidelines/indications and patient condition, including but not limited to PD-1 inhibitors, PD-L1 inhibitors.~Fruquintinib: 3mg (starting dose), PO (once daily). Dosing schedule and dosage can be adjusted based on concurrent chemotherapy and immune checkpoint inhibitors. Have received fruquintinib treatment for at least 2 cycles."

Trial Locations (1)

430000

Zhongnan Hospital of Wuhan University, Wuhan

All Listed Sponsors
lead

Wuhan University

OTHER