60
Participants
Start Date
July 5, 2024
Primary Completion Date
June 30, 2027
Study Completion Date
June 30, 2027
Irinotecan Hydrochloride Liposome Injection;Carboplatin Injection;Serplulimab Injection
"Cohort 1: Liposomal irinotecan: 50mg/m2, ivgtt, d1; Carboplatin AUC=5, ivgtt, d1; Serplulimab: 4.5mg/kg, ivgtt, d1; The drug was administered once every three weeks for a total of 4 cycles. After 4 cycles, serplulimab is maintained until disease progression or toxicity becomes intolerable.~Cohort 2: Etoposide: 100 mg/m2, ivgtt, d1-3; Carboplatin AUC=5, ivgtt, d1; Serplulimab: 4.5mg/kg, ivgtt, d1; The drug was administered once every three weeks for a total of 4 cycles. After 4 cycles, serplulimab is maintained until disease progression or toxicity becomes intolerable."
Sun Yat-sen University
OTHER
Hunan Cancer Hospital
OTHER
Guangdong Provincial Hospital of Traditional Chinese Medicine
OTHER
First People's Hospital of Foshan
OTHER
Youjiang Medical College for Nationalities
OTHER
Zhou Chengzhi
OTHER