Efficacy and Safety of Anti-PD-1, Thymalfasin, and SOX in Neoadjuvant Treatment of cStage III Gastric/Gastroesophageal Junction Adenocarcinoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

June 14, 2024

Primary Completion Date

May 31, 2025

Study Completion Date

December 31, 2027

Conditions
Gastric CancerEsophagogastric Junction Adenocarcinoma
Interventions
DRUG

Serplulimab

200 mg, i.v., D1, Q3W

DRUG

thymalfasin

4.8mg,sc,biw

DRUG

Oxaliplatin

130 mg/m2, i.v., D1, Q3W

DRUG

Tegafur

oral administration: body surface area \< 1.25, 40 mg each time; body surface area ≥ 1.25 to \< 1.5, 50 mg each time; body surface area ≥ 1.5, 60 mg each time, twice daily for each treatment cycle at D1-D14

Trial Locations (1)

Unknown

RECRUITING

The First Hospital of Nanjing Medical University, Nanjing

All Listed Sponsors
lead

Zekuan Xu

OTHER