A PROspective Faecal MIcrobiota tranSplantation Trial to Improve outcomEs in Patients With Cirrhosis

PHASE3RecruitingINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

June 21, 2023

Primary Completion Date

November 30, 2026

Study Completion Date

April 30, 2027

Conditions
Liver Cirrhosis
Interventions
DRUG

Encapsulated FMT

Encapsulated Faecal Microbiota Transplant

OTHER

Placebo

The placebo product contains microcrystalline methylcellulose. It is supplied as a size 0, Swedish Orange Delayed-Release capsule (DRCap) and provides a complete match with regards to the appearance (e.g., dimensions, colour) to the FMT capsules.

Trial Locations (16)

BH7 7DW

NOT_YET_RECRUITING

Royal Bournemouth Hospital, Bournemouth

BS10 5NB

RECRUITING

Southmead Hospital, Bristol

BS2 8HW

RECRUITING

Bristol Royal Infirmary, Bristol

DE22 3NE

RECRUITING

Royal Derby Hospital, Derby

DD1 9SY

RECRUITING

Ninewells Hospital, Dundee

NE9 6SX

RECRUITING

Queen Elizabeth Hospital, Gateshead

G51 4TF

RECRUITING

Queen Elizabeth University Hospital, Glasgow

HU3 2JZ

RECRUITING

Hull Royal Infirmary, Hull

LS9 7TF

RECRUITING

St. James University Hospital, Leeds

SE5 9RS

RECRUITING

King's College Hospital NHS Foundation Trust, London

SW17 0QT

RECRUITING

St. George's University Hospital NHS Foundation Trust, London

W2 1NY

RECRUITING

St. Mary's Hospital, London

NE7 7DN

RECRUITING

Freeman Hospital, Newcastle upon Tyne

NP20 2UB

RECRUITING

Royal Gwent Hospital, Newport

NG7 2UH

RECRUITING

Queen's Medical Centre, Nottingham

PL6 8DH

RECRUITING

Derriford Hospital, Plymouth

All Listed Sponsors
collaborator

St George's, University of London

OTHER

collaborator

Guy's and St Thomas' NHS Foundation Trust

OTHER

collaborator

Imperial College London

OTHER

collaborator

King's College Hospital NHS Trust

OTHER

collaborator

BRITISH LIVER TRUST

UNKNOWN

lead

King's College London

OTHER