90
Participants
Start Date
October 14, 2024
Primary Completion Date
May 26, 2027
Study Completion Date
July 9, 2027
Cenobamate
"The 100 mg/ day Treatment Period includes a 6-week Titration Phase and a 26-week Maintenance Phase. During the Titration Phase subjects will be treated with cenobamate 12.5 mg/day for two weeks, 25 mg/day for two weeks and 50 mg/day for two weeks. Subjects tolerating cenobamate at the end of the Titration Phase will continue treatment with 100 mg/day in the Maintenance Phase for 26 weeks. If the subject does not experience a certain type of seizure in the 100 mg/day Maintenance Phase, he/she can enter the Optional Extension Period (100 mg/day).~The 200 mg/day treatment period consists of a 2-week Titration Phase and a 26-week Maintenance Phase. During the 2-week Titration Phase, subjects will receive cenobamate 150 mg/day before entering the 26-week 200 mg/day Maintenance Phase. If the subject does not experience a certain type of seizure during the 200 mg/day Maintenance Phase, he/she can enter the 26 week Optional Extension Period (200 mg/day)."
RECRUITING
NY Neurology Associates, New York
RECRUITING
Mount Sinai Hospital, New York
RECRUITING
Allegheny Neurological Associates, Pittsburgh
RECRUITING
Thomas Jefferson University, Philadelphia
RECRUITING
The George Washington University Hospital, Washington D.C.
RECRUITING
Midatlantic Epilepsy and Sleep Center, Bethesda
RECRUITING
John Hopkins Epilepsy Center, Baltimore
RECRUITING
Virginia Epilepsy and Neurodevelopmental Clinic, Winchester
RECRUITING
Augusta University, Augusta
RECRUITING
Knight Neurology, Rockledge
RECRUITING
Elite Clinical Research, Miami
WITHDRAWN
Serenity Research Center, Miami
WITHDRAWN
Neurology Consultants of Central Florida, Kissimmee
RECRUITING
Vanderbilt Epilepsy Clinic, Nashville
RECRUITING
Bluegrass Epilepsy Research LLC, Lexington
RECRUITING
Ohio Health Research Institute, Columbus
RECRUITING
Wayne Neurology PLC, Plymouth
RECRUITING
Henry Ford Health System, Detroit
RECRUITING
Froedtert and The Medical College of Wisconsin, Milwaukee
RECRUITING
Minnesota Epilepsy Group, Roseville
RECRUITING
RUSH Neurology Epilepsy, Chicago
RECRUITING
University of Missouri Health Care, Columbia
RECRUITING
The University of Kansas Hospital, Kansas City
WITHDRAWN
New England Institute for Clinical Research, Chalmette
RECRUITING
Louisiana State University Health Sciences, Shreveport
RECRUITING
Clinical Trials Inc, Little Rock
WITHDRAWN
Northwest Houston Neurology, Cypress
RECRUITING
DHR Health Institute for Research and Development, Edinburg
RECRUITING
Consultants In Epilepsy and Neurology, Boise
RECRUITING
University of Utah, Salt Lake City
RECRUITING
Arizona Neuroscience Research, Phoenix
RECRUITING
Center For Neurosciences, Tucson
RECRUITING
Rancho Los Amigos National Rehabilitation Center, Downey
RECRUITING
Hoag Physician Partners, Newport Beach
RECRUITING
Neuro Pain Medical Center, Fresno
RECRUITING
Hartford Hospital, Hartford
RECRUITING
Yale School of Medicine - Yale-New Haven Hospital, New Haven
WITHDRAWN
Neurology Center of New England P.C., Foxborough
RECRUITING
Northeast Regional Epilepsy Group, Hackensack
RECRUITING
Overlook Medical Center, Summit
SK Life Science, Inc.
INDUSTRY