60
Participants
Start Date
June 6, 2024
Primary Completion Date
June 1, 2025
Study Completion Date
June 1, 2027
Induction immunochemotherapy followed by Adebrelimab plus concurrent chemoradiotherapy
"Induction immunochemotherapy:~Nab-paclitaxel:220mg/m2,IV,d1,d22; Carboplatin:AUC=5,IV,d1,d22; Adebrelimab:1200mg, IV,d1, d22.~Evaluation of the Curative Effect:CR+PR~Adebrelimab plus concurrent chemoradiotherapy:~Adebrelimab:1200mg, IV,q3w, until PD; Nab-paclitaxel:175mg/m2,IV,d1,d22; Carboplatin:AUC=5,IV,d1,d22; Radiotherapy:50.4Gy/1.8Gy/28f."
Induction immunochemotherapy followed by concurrent chemoradiotherapy
"Induction immunochemotherapy:~Nab-paclitaxel:220mg/m2,IV,d1,d22; Carboplatin:AUC=5,IV,d1,d22; Adebrelimab:1200mg, IV,d1, d22.~Evaluation of the Curative Effect:SD+PD~Concurrent chemoradiotherapy:~Oxaliplatin:85 mg/m2,IV,d1,d15,d29; Leucovorin:400mg/m2,IV,d1,d15,d29; 5-FU:400mg/m2,IV,d1,d15,d29; 5-FU:1600mg/m2,CIV48h,d1,d15,d29; Radiotherapy:PTV/PGTV:50.4Gy/59.92Gy/28f."
Tianjin Cancer Hospital, Tianjin
Tianjin Medical University Cancer Institute and Hospital
OTHER