Cerebral and Anti-inflammatory Response Through Exercise - Mechanisms in Depressive Disorders

NANot yet recruitingINTERVENTIONAL
Enrollment

124

Participants

Timeline

Start Date

April 21, 2025

Primary Completion Date

September 1, 2026

Study Completion Date

December 31, 2026

Conditions
Major Depressive DisorderInflammatory Response
Interventions
OTHER

Physical Exercise

"Daily walking. Participants will be given an activity band to self-monitor the number of steps they walk each day during the 12-week intervention period. Each participant must reach a certain number of daily steps with a progressive goal adjusted to the number of steps from the previous week. The goal is set considering the superior number to the median of steps of the preceding week.~Weekly combined exercise sessions (aerobic + strength exercise) 2 sessions of 60 minutes per week in a 12-week program. The exercise intervention will combine the use of elastic bands and the body weight. First, 5 minutes of warm-up; second, training circuit with low-intensity strength exercises alternating work and rest times using rhythmic music. Upper, lower and middle body exercises will alternate. The program will progress in intensity, work: rest ratio, and technical difficulty of the exercises. At the end of the main part, there will be a cool-down and stretching for 5 minutes."

Trial Locations (4)

28006

Hospital Universitario de La Princesa, Madrid

28034

Hospital Universitario Ramón y Cajal, Madrid

28046

Hospital Universitario La Paz, Madrid

28805

Hospital Universitario Príncipe de Asturias, Madrid

All Listed Sponsors
collaborator

Hospital Universitario La Paz

OTHER

collaborator

Hospital Universitario Ramon y Cajal

OTHER

collaborator

Hospital Universitario Principe de Asturias

OTHER

collaborator

Quirón Madrid University Hospital

OTHER

collaborator

Universidad Autonoma de Madrid

OTHER

collaborator

Centro de Investigación Biomédica en Red de Salud Mental

NETWORK

lead

Fundación de Investigación Biomédica - Hospital Universitario de La Princesa

OTHER

NCT06450704 - Cerebral and Anti-inflammatory Response Through Exercise - Mechanisms in Depressive Disorders | Biotech Hunter | Biotech Hunter