A Trial to Compare Nebulized Amphotericin B and Nebulized Normal Saline as Maintenance in Patients With Chronic Pulmonary Aspergillosis

PHASE3RecruitingINTERVENTIONAL
Enrollment

196

Participants

Timeline

Start Date

June 3, 2024

Primary Completion Date

June 3, 2026

Study Completion Date

August 31, 2026

Conditions
Chronic Pulmonary AspergillosisCPAAspergilloma
Interventions
DRUG

Normal saline

5 mL of normal saline will be nebulised in the control arm

DRUG

Amphotericin B deoxycholate

2 mL of the above reconstituted amphotericin B solution will be obtained in a sterile syringe and transferred into the drug chamber of a nebulizer. Three mL of distilled water will be added to 2 mL of the reconstituted amphotericin B (5 mL liquid in the chamber ensures complete and easy nebulization of all the contents)

Trial Locations (1)

160012

RECRUITING

Chest clinic, Chandigarh

All Listed Sponsors
lead

Post Graduate Institute of Medical Education and Research, Chandigarh

OTHER