30
Participants
Start Date
April 12, 2024
Primary Completion Date
May 31, 2027
Study Completion Date
October 31, 2027
Mitoxantrone hydrochloride liposome
Veneclatra (VEN) 400 mg/d (reduced to 100 mg when combined with an azole), d1-7; Mitoxantrone Liposomal 30 mg/m2, d1; Cytosine arabinoside(Ara-C) 100 mg/m2/d, d1-7; Cyclophosphamide (CTX) 400 mg/m2/d, d2, 5); After 1 day of rest, cryopreserved donor stem cells MNC1-2X10\^8 /kg infusion, add low-dose (25 mg Bid) and short-course treatment (stop 2-3 weeks after DLI) oral cyclosporine (CSA) to prevent graft-versus-host disease (GVHD) 3 days before cryopreserved stem cell infusion.
RECRUITING
Institute of Hematology & Blood Diseases Hospital, China, Tianjin
Institute of Hematology & Blood Diseases Hospital, China
OTHER