A Dose Escalating Study of CD19/CD22/BCMA CAR-T Therapy in Relapsed or Refractory B Cell Non-Hodgkin Lymphoma(NHL)

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

May 7, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Non-Hodgkin Lymphoma, B-cell
Interventions
BIOLOGICAL

CD19/CD20/BCMA CAR T cells

"Subjects will undergo leukapheresis to isolate peripheral blood mononuclear cells (PBMCs) for the production of CD19/CD20/BCMA CAR T cells.~Cyclophosphamide and fludarabine will be given from day-5 to day-3 before the infusion for lymphodepletion. On day0 subjects will receive one dose treatment with CD19/CD20/BCMA CAR T cells by intravenous (IV) injection"

Trial Locations (1)

201800

RECRUITING

Mengchao Cancer Hospital, Shanghai

All Listed Sponsors
lead

Shanghai Cell Therapy Group Co.,Ltd

INDUSTRY