Post-operative Radiotherapy Omission in Selected Patients With Early Breast Cancer Trial International VErsion (PROSPECTIVE)

NARecruitingINTERVENTIONAL
Enrollment

1,400

Participants

Timeline

Start Date

June 6, 2025

Primary Completion Date

June 30, 2032

Study Completion Date

June 30, 2039

Conditions
Breast CancerBreast Cancer Female
Interventions
RADIATION

Arm A: Radiotherapy Omission

Omission of radiotherapy based on pre-surgical MRI and pathology findings at surgery.

OTHER

Arm B: Standard Treatment

Ineligible for RT omission on study; includes management of MRI-detected lesions.

Trial Locations (7)

2050

NOT_YET_RECRUITING

The Chris O'Brien Lifehouse, Camperdown

2060

NOT_YET_RECRUITING

Mater Hospital, Sydney, North Sydney

2145

NOT_YET_RECRUITING

Westmead Hospital, Westmead

2290

NOT_YET_RECRUITING

Lake Macquarie Private Hospital, Gateshead

3000

RECRUITING

The Royal Melbourne Hospital, Melbourne

3168

NOT_YET_RECRUITING

Monash Cancer Centre (MMC Moorabbin), Clayton

5000

NOT_YET_RECRUITING

Royal Adelaide Hospital, Adelaide

All Listed Sponsors
lead

Breast Cancer Trials, Australia and New Zealand

OTHER

NCT06445738 - Post-operative Radiotherapy Omission in Selected Patients With Early Breast Cancer Trial International VErsion (PROSPECTIVE) | Biotech Hunter | Biotech Hunter