Rebuilding Inter-limb Transfer in Cervical SCI

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

17

Participants

Timeline

Start Date

February 15, 2024

Primary Completion Date

July 30, 2026

Study Completion Date

July 30, 2026

Conditions
Cervical Spinal Cord Injury
Interventions
DEVICE

PCMS + Contralateral Motor Training

PCMS + Contralateral Motor Training will involve delivering 360 pairs of TMS-PNS pulses (30min, 0.2 Hz) to the weaker first dorsal interosseous (FDI) muscle immediately before a session of ballistic index finger abduction training at the opposite, stronger FDI muscle.

DEVICE

PCMS + Rest

PCMS + Rest will involve delivering 360 pairs of TMS-PNS pulses (30min, 0.2Hz) to the weaker FDI followed by a 30-min rest.

DEVICE

Sham PCMS + Contralateral Motor Training

360 TMS pulses will be delivered at a location 10-cm posterior to the participant's head (into the air, 0.2Hz) and no PNS pulses will be generated, followed by a session of 30-min ballistic index finger abduction training at the opposite, stronger FDI muscle.

Trial Locations (1)

44195

RECRUITING

Lerner Research Institute; Cleveland Clinid Foundation, Cleveland

All Listed Sponsors
collaborator

The Craig H. Neilsen Foundation

OTHER

lead

The Cleveland Clinic

OTHER