Interleukin-2 (IL-2), Interleukin-5 (IL-5) and Interleukin-17 (IL-17) Levels of Patients With Stainless Steel Crowns

CompletedOBSERVATIONAL
Enrollment

12

Participants

Timeline

Start Date

September 10, 2024

Primary Completion Date

November 1, 2024

Study Completion Date

April 15, 2025

Conditions
SalivaDental CrownNickel Sensitivity
Interventions
GENETIC

Salivary Collection

Expression levels of IL-2, IL-5 and IL-17 in the saliva of individuals aged 3-9 years who underwent stainless steel crown will be recorded before and after the procedure. Before the saliva sample collection procedure, the patient will be asked to rinse their mouth with sterile water and then spit into sterile plastic cups. After collecting approximately 3 ml of saliva, the saliva will be transferred to appropriate eppendorfs and stored at -40 degrees Celsius. For the second post-procedure, the same algorithms will be applied for saliva collection seven days after the crown procedure.

DIAGNOSTIC_TEST

Ph and ion level measurement of saliva

Salivary concentration of nickel, chrome ions will be measured using an atomic absorption spectrophotometer.

Trial Locations (1)

65080

Yüzüncü Yil University, Van

All Listed Sponsors
lead

Yuzuncu Yıl University

OTHER

NCT06439095 - Interleukin-2 (IL-2), Interleukin-5 (IL-5) and Interleukin-17 (IL-17) Levels of Patients With Stainless Steel Crowns | Biotech Hunter | Biotech Hunter