A Study of B013 in Combination With Paclitaxel in Patients With Platinum-resistant Recurrent Ovarian Cancer.

PHASE2RecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

July 11, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Platinum-resistant Recurrent Ovarian Cancer
Interventions
DRUG

B013

B013: The subjects will receive IV dose of B013 600 mg on Day 1 and 15 of the first 28-day cycle, then on Day 1 of each subsequent 28-day cycle.

DRUG

Paclitaxel

Paclitaxel: 80 mg/m\^2 is administered weekly on Day 1, 8, 15 of each 28-day cycle.

DRUG

Placebo

Placebo: The subjects will receive IV dose of placebo matched to B013 on Day 1 and 15 of the first 28-day cycle, then on Day 1 of each subsequent 28-day cycle.

Trial Locations (17)

Unknown

RECRUITING

Beijing Cancer Hospital, Beijing

RECRUITING

The First Affiliated Hospital of Bengbu Medical University, Bengbu

RECRUITING

XiangYa Hospital CentralSouth University, Changsha

RECRUITING

Fujian Cancer Hospital, Fuzhou

RECRUITING

Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou

RECRUITING

Cancer Hospital of Shandong First Medical University, Jinan

RECRUITING

Qilu Hospital of Shandong University, Jinan

RECRUITING

Yunnan Cancer Hospital, Kunming

RECRUITING

Guangxi Medical University Cancer Hospital, Nanning

RECRUITING

Fudan University Shanghai Cancer center, Shanghai

RECRUITING

The Obstetrics & Gynecology Hospital of Fudan University, Shanghai

RECRUITING

The Second Hospital of Hebei Medical University, Shijiazhuang

RECRUITING

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

RECRUITING

Shananxi Provincial Cancer Hospital, Xi'an

RECRUITING

The First Affiliated Hospital of Xiamen University, Xiamen

RECRUITING

Yibin city second people's Hospital, Yibin

RECRUITING

Henan Cancer Hospital, Zhengzhou

All Listed Sponsors
collaborator

Shanghai Pharmaceuticals Holding Co., Ltd

INDUSTRY

lead

Shanghai Jiaolian Drug Research and Development Co., Ltd

INDUSTRY