Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma

PHASE1RecruitingINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

August 22, 2024

Primary Completion Date

July 31, 2026

Study Completion Date

July 31, 2026

Conditions
Relapsed Multiple MyelomaRefractory Multiple Myeloma
Interventions
DRUG

OPN-6602

orally active, small molecule inhibitor of EP300 and CBP bromodomain; dosed daily

DRUG

Dexamethasone

Synthetic glucocorticoid; 40 mg Days 1, 8, 15 of each cycle

Trial Locations (10)

14642

RECRUITING

University of Rochester Medical Center, Rochester

30322

RECRUITING

Emory Winchip Cancer Center, Atlanta

48201

RECRUITING

Karmanos Cancer Institute, Detroit

49546

RECRUITING

START Midwest, Grand Rapids

66205

RECRUITING

University of Kansas Clinical Research Center, Westwood

84112

RECRUITING

Huntsman Cancer Center Institute University of Utah, Salt Lake City

85234

RECRUITING

Banner MD Anderson, Gilbert

94305

RECRUITING

Stanford Cancer Institute, Stanford

98109

RECRUITING

Fred Hutchinson Cancer Center, Seattle

02215

RECRUITING

Dana Farber Cancer Institute, Boston

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Opna Bio LLC

INDUSTRY