A Study to Compare the Relative Potency of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152a to HFA-134a in Mild Asthmatics Aged 18 to 65 Inclusive

PHASE1RecruitingINTERVENTIONAL
Enrollment

91

Participants

Timeline

Start Date

August 14, 2024

Primary Completion Date

August 14, 2026

Study Completion Date

August 14, 2026

Conditions
AsthmaMild Asthma
Interventions
DRUG

Salbutamol HFA-152a

A single 100, 200 or 400 μg dose, given as 1, 2 or 4 × 100 μg actuations (exvalve) at 20 second intervals.

DRUG

Salbutamol HFA-134a

A single 100, 200 or 400 μg dose, given as 1, 2 or 4 × 100 μg actuations (exvalve) at 20 second intervals.

DRUG

Placebo

A single placebo HFA-152a suspension or placebo HFA-134a suspension dose, given as at 20 second intervals.

Trial Locations (1)

M23 9QZ

RECRUITING

GSK Investigational Site, Manchester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

GlaxoSmithKline

INDUSTRY