NCT06427421View on ClinicalTrials.gov

Characterization of Autoreactive Regulatory and Conventional CD4 T Cells in Recent Onset Type 1 Diabetes and Control Individuals

NANot yet recruitingINTERVENTIONAL

Enrollment

80

Participants

Timeline

Start Date

June 30, 2024

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2026

Conditions

Type 1 Diabetes

Interventions

BIOLOGICAL

Frequency of Treg and Teffs

additionnal blood sampling at inclusion

BIOLOGICAL

Phenotype of Treg and Teffs

additionnal blood sampling at inclusion

BIOLOGICAL

RNA seq analysis

additionnal blood sampling at inclusion

BIOLOGICAL

HLA typing

additionnal blood sampling at inclusion

BIOLOGICAL

beta-cell autoantibody dosage

additionnal blood sampling at inclusion

BIOLOGICAL

Glycated haemoglobin (HbA1C) dosage

additionnal blood sampling at inclusion

BIOLOGICAL

blood glucose dosage

additionnal blood sampling at inclusion

BIOLOGICAL

C-peptide dosage

additionnal blood sampling at inclusion

Trial Locations (1)

75015

Hôpital Necker Enfants Malades, Paris

All Listed Sponsors

lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT06427421 - Characterization of Autoreactive Regulatory and Conventional CD4 T Cells in Recent Onset Type 1 Diabetes and Control Individuals | Biotech Hunter | Biotech Hunter