5,400
Participants
Start Date
June 1, 2024
Primary Completion Date
December 20, 2024
Study Completion Date
December 30, 2024
Mosquirixs
RTS,S is a subunit vaccine that includes a portion of the circumsporozoite protein (CSP) co-expressed with Hepatitis B surface antigen. The adjuvant is AS01. Three doses of the vaccine will be administered, each with one month interval.
artemether-lumefantrine
A therapeutic dose of artemether-lumefantrine (20 mg of artemether and 120 mg of lumefantrine) will be given twice a day for 3 days based on the weight of the child as per treatment guidelines.
Ministry of Health, Malawi
OTHER_GOV
Boston University
OTHER
Michigan State University
OTHER
Kamuzu University of Health Sciences
OTHER