NCT06420349 - NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

May 31, 2024

Primary Completion Date

May 31, 2026

Study Completion Date

May 31, 2026

Conditions

Advanced CholangiocarcinomaMetastatic CholangiocarcinomaRefractory CholangiocarcinomaStage III Hilar Cholangiocarcinoma AJCC v8Stage III Intrahepatic Cholangiocarcinoma AJCC v8Stage IV Hilar Cholangiocarcinoma AJCC v8Stage IV Intrahepatic Cholangiocarcinoma AJCC v8

Interventions

PROCEDURE

Biospecimen Collection

Undergo collection of blood samples

PROCEDURE

Computed Tomography

Undergo CT

BIOLOGICAL

Heat Shock Factor 1 Pathway Inhibitor NXP800

Given PO

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

PROCEDURE

Positron Emission Tomography

Undergo PET

PROCEDURE

Ultrasound-Guided Biopsy

Undergo ultrasound-guided tumor biopsy

Trial Locations (2)

55905

RECRUITING

Mayo Clinic in Rochester, Rochester

85259

RECRUITING

Mayo Clinic in Arizona, Scottsdale