Prediction of Radiotherapy Efficacy in Patients With Triple-negative Breast Cancer

NARecruitingINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

January 11, 2024

Primary Completion Date

April 1, 2027

Study Completion Date

April 1, 2027

Conditions
Triple-negative Breast Cancer
Interventions
BIOLOGICAL

blood sampling before radiotherapy

A blood sample (20 ml) will be taken prior to radiotherapy

BIOLOGICAL

blood sampling after the fourth radiotherapy session

A blood sample (20 ml) will be taken immediately after the 4th radiotherapy session.

OTHER

collection of acute toxicity (radiodermatitis)

for the entire duration of radiotherapy

OTHER

collection of late toxicity

every year for 5 years

OTHER

collection of disease status

throughout the study

RADIATION

Radiotherapy - Breast +/- lymph node areas

40.05 Gy in 15 fractions of 2.67 Gy, one fraction per week, 5 days per week Or 50 Gy in 25 fractions of 2 Gy, one fraction per week, 5 days per week

RADIATION

Radiotherapy - Boost operating bed

10 Gy in 4 fractions of 2.5 Gy, one fraction per week, 5 days per week Or 16 Gy in 8 fractions of 2 Gy, one fraction per week, 5 days per week

Trial Locations (1)

67033

RECRUITING

Institut de cancérologie Strasbourg europe, Strasbourg

All Listed Sponsors
collaborator

Centre de recherche du Centre hospitalier universitaire de Sherbrooke

OTHER

lead

Institut de cancérologie Strasbourg Europe

OTHER