2,000
Participants
Start Date
March 1, 2025
Primary Completion Date
December 31, 2026
Study Completion Date
December 31, 2027
Dexmedetomidine
The 200ug dexmedetomidine will be diluted into a 50ml syringe and administered with 0.4ug/kg/h intraoperatively and 0.05 μg/kg/h for 48 hours after surgery.
Normal saline
In the placebo group, the 0.9% saline is administered with the same volume at the same speed as the dexmedetomidine group
Local analgesic techniques
The 10ml 1% ropivacaine will be diluted into a 20ml syringe . As for scalp nerve block, each nerve will be blocked separately with 1-2 mL 0.5% ropivacaine.
no Local analgesic techniques
No Local analgesic techniques will be given.
Beijing Tiantan Hospital
OTHER