"Evaluation of the Efficacy of Dd-cfDNA in Routine Patient Care in Kidney Transplant Recipients"

NARecruitingINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

May 31, 2025

Primary Completion Date

November 30, 2028

Study Completion Date

November 30, 2028

Conditions
Renal Transplantation
Interventions
BIOLOGICAL

dd-cfDNA-guided

"In groups I and II, the blood sample for dd-cfDNA assay will be taken on D0, just prior to transplantation, for all patients.~in addition, for patients following a dd-cf DNA-guided strategy based on dd-cf DNA ; samples for dd-cf DNA assay will be taken at M3 and M12 visits and at visits for clinical indication (5 maximum) and the blood will be sent to the PARCC technical platform of INSERM UMR 970. By combining the dd-cfDNA level and relevant medical data, an integration report will be sent to the centers to stratify patients into high-risk or low-risk rejection profiles.~If the patient is classified in the low risk of rejection subgroup, he may decide not to perform the biopsy. If the patient is classified in the high risk of rejection subgroup, he may decide to perform the biopsy within 15 days of the sample being taken. the decision to perform the biopsy is left to the discretion of the physician."

Trial Locations (6)

75010

RECRUITING

Hopital Saint Louis, Paris

75013

RECRUITING

Hôpital de la Salpêtrière hôpital à Paris, Paris

75015

ACTIVE_NOT_RECRUITING

Georges Pompidou European Hospital, Paris

ACTIVE_NOT_RECRUITING

Hôpital Necker-Enfants Malades, Paris

Unknown

ACTIVE_NOT_RECRUITING

AP-HP - Hôpital Tenon, Paris

NOT_YET_RECRUITING

CHU Toulouse, Toulouse

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT06406179 - "Evaluation of the Efficacy of Dd-cfDNA in Routine Patient Care in Kidney Transplant Recipients" | Biotech Hunter | Biotech Hunter