Transcutaneous Vagus Nerve Stimulation in Aphasia After Stroke

NARecruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

April 25, 2024

Primary Completion Date

June 3, 2026

Study Completion Date

January 1, 2027

Conditions
AphasiaChronic Stroke
Interventions
DEVICE

Transcutaneous Vagus Nerve Stimulation

"Transcutaneous auricular vagus nerve stimulation using the Nurosym (Parasym Ltd) device.~Stimulation parameters:~Pulse width: 250µs; Frequency: 25Hz; Intensity: Below pain threshold.~The active stimulation will be delivered to the left tragus. Participants will complete the intervention at home once they have received sufficient training on how to use the stimulation device."

DEVICE

Sham Transcutaneous Vagus Nerve Stimulation

Stimulation will be delivered at the same parameters however, sham stimulation will be delivered to the left earlobe. Earlobe stimulation has been used as a sham in other studies as it is not thought to activate the vagus nerve.

BEHAVIORAL

Computer Based Speech and Language Therapy (Step by Step)

Computer-based Speech and Language Therapy will be completed whilst wearing the stimulation device in all groups. The Step by Step programme uses an errorless learning approach to practice naming. All participants will practice a set of 30 meaningful words during the intervention. Participants will complete the SLT programme at home on an ipad, whilst using the stimulation device.

Trial Locations (1)

S10 2JF

RECRUITING

Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield

All Listed Sponsors
lead

Sheffield Teaching Hospitals NHS Foundation Trust

OTHER