Radiation Dosimetry of the 18 kDa Translocator Protein Ligand [18F]PBR111 in Humans

NACompletedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

June 24, 2024

Primary Completion Date

July 30, 2024

Study Completion Date

July 30, 2024

Conditions
DosimetryHealthy
Interventions
DRUG

[18F]PBR111

\[18F\]PBR111 is a radiotracer produced at University Hospital of Geneva in a radiopharmaceutical GMP facility. The drug product is provided as sterile solution for intravenous injection in a glass vial containing 10 mL (max) of formulated product, the maximal applicable dose being 200 MBq.

PROCEDURE

PBR111 injection

\[18F\]PBR111 will be administered once, intravenously in the antecubital fossa at a dose of 200 MBq

DEVICE

PET scan

Upon administration of the radiotracer, a 120-minute PET/CT scan will be initiated.

RADIATION

PBR111 dosimetry

to establish the exposure of the organs/tissues to a standard radioactive dose (200 MBq) of \[18F\]PBR111

Trial Locations (1)

Unknown

Geneva University Hospital, Geneva

All Listed Sponsors
lead

Prof. Daniele Zullino

OTHER

NCT06398392 - Radiation Dosimetry of the 18 kDa Translocator Protein Ligand [18F]PBR111 in Humans | Biotech Hunter | Biotech Hunter