Efficacy and Safety Assessment of T4090 Ophthalmic Solution Versus Rhopressa® Ophthalmic Solution in Patients with Open-angle Glaucoma or Ocular Hypertension

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

126

Participants

Timeline

Start Date

August 5, 2024

Primary Completion Date

May 31, 2025

Study Completion Date

May 31, 2025

Conditions
GlaucomaOcular Hypertension
Interventions
DRUG

T4090 0.2%

1 drop in the conjunctival cul-de-sac of each eye once daily at 8:00 PM (±1 hour) from Day 1 to the day before the End of treatment visit (Visit #5 - Week 7).

DRUG

T4090 0.3%

1 drop in the conjunctival cul-de-sac of each eye once daily at 8:00 PM (±1 hour) from Day 1 to the day before the End of treatment visit (Visit #5 - Week 7).

DRUG

Rhopressa®

1 drop in the conjunctival cul-de-sac of each eye once daily at 8:00 PM (±1 hour) from Day 1 to the day before the End of treatment visit (Visit #5 - Week 7).

Trial Locations (24)

12603

Alterman, Modi and Wolter Ophthalmic Surgeons, Poughkeepsie

21078

Seidenberg Protzko Eye Associates, Havre de Grace

22046

Emerson Clinical Research Institute, Falls Church

24502

Piedmont Eye Center, Lynchburg

27101

James D. Branch, MD, Winston-Salem

30076

Coastal Research Associates, LLC, Roswell

32256

East Coast Institute for Research, LLC, Jacksonville

32757

Mild Florida Eye Center, Mt. Dora

33484

Segal Drug Trials, Inc, Delray Beach

33773

Shettle Eye Research, Inc., Largo

38119

Total Eye Care, PA, Memphis

53719

Houston Eye Associates, Houston

75231

Glaucoma Associates of Texas, Dallas

77008

Houston Eye Associates, Houston

78572

DCT-Shah Research, LLC sba Discovery Clinical Trials, Mission

78731

Keystone Research, Austin

85306

Arizona Advanced Eye Research Institute, Glendale

90301

United Medical Research Institute, Inglewood

90505

Wolstan and Goldberg Eye Associates, Torrance

91204

Global Research Management, Inc., Glendale

92663

Eye Research Foundation, Newport Beach

Visionary Research Institute, Newport Beach

94954

North Bay Eye Associates, Petaluma

95815

Sacramento Eye Consultants, A Medical Corporation, Sacramento

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Laboratoires Thea

INDUSTRY

NCT06394973 - Efficacy and Safety Assessment of T4090 Ophthalmic Solution Versus Rhopressa® Ophthalmic Solution in Patients with Open-angle Glaucoma or Ocular Hypertension | Biotech Hunter | Biotech Hunter