PCSK9 Inhibitors in Combination With Advanced Treatment Strategies for the Treatment of Advanced Colorectal Cancer With pMMR/MSS

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

May 6, 2024

Primary Completion Date

April 6, 2028

Study Completion Date

May 6, 2028

Conditions
Colorectal Cancer
Interventions
DRUG

PCSK9 inhibitor in combination with standard advanced first-line regimen group

Fluorouracil and platinum as the base chemotherapy regimen, with or without targeted therapy, was administered subcutaneously at a fixed dose of 150 mg of PCSK9 inhibitor every two weeks starting on day 1 of patient enrollment

DRUG

standard advanced first-line regimen group

Fluorouracil and platinum were used as the basic chemotherapy regimens, with or without targeted therapy, and no additional injection of PCSK9 inhibitors

All Listed Sponsors
lead

Guangdong Provincial People's Hospital

OTHER

NCT06391905 - PCSK9 Inhibitors in Combination With Advanced Treatment Strategies for the Treatment of Advanced Colorectal Cancer With pMMR/MSS | Biotech Hunter | Biotech Hunter