150
Participants
Start Date
January 1, 2021
Primary Completion Date
December 31, 2023
Study Completion Date
December 31, 2023
esmolol
The primary intervention is the administration of Esmolol. Esmolol was specifically used to evaluate its immunomodulatory effects in patients with sepsis in the study. The dosage was tailored to achieve optimal heart rate control, an integral part of the therapeutic strategy aiming to mitigate the hyperadrenergic state often seen in sepsis. Alongside Esmolol, daily electrocardiogram (ECG) monitoring was incorporated to observe any changes in the QT interval, ensuring cardiac safety due to the known potential cardiac effects of beta-blockers.
Sichuan Provincial People's Hospital, Chengdu
Lead Sponsor
Lin Chen
OTHER