Neoadjuvant Lu-PSMA Radioligand Therapy and Ipilimumab in Men With Very High-risk Prostate Cancer

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

May 31, 2024

Primary Completion Date

March 31, 2027

Study Completion Date

September 30, 2028

Conditions
Very High Risk Prostate Carcinoma
Interventions
RADIATION

[177Lu]Lu-PSMA-617

2 cycles of 7,4 GBq \[177Lu\]Lu-PSMA-617 at 6 weeks intervals

DRUG

Ipilimumab

4 cycles of Ipilimumab 3mg/kg at 3 weeks intervals

Trial Locations (1)

45147

University Hospital Essen, Clinic of Urology, Essen

All Listed Sponsors
collaborator

Advanced Accelerator Applications

INDUSTRY

collaborator

Bristol-Myers Squibb

INDUSTRY

lead

University Hospital, Essen

OTHER