Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping

PHASE4RecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

February 19, 2024

Primary Completion Date

June 30, 2027

Study Completion Date

January 31, 2028

Conditions
Moderate to Severe Asthma
Interventions
BIOLOGICAL

Dupilumab

"Dupilumab, an interleukin-4 receptor treatment, will be administered through a subcutaneous injection, the initial dose of 600 mg will be administered at two different injection sites (300 mg per injection), followed by a single dose of 300 mg administered every other week (Q2W).~Participants may self-administer injection after proper training."

BIOLOGICAL

Benralizumab

"Benralizumab, an interleukin-5 receptor treatment, will be administered through a subcutaneous injection every 4 weeks (Q4W).~Participants may self-administer injection after proper training."

Trial Locations (3)

85259

RECRUITING

Mayo Clinic, Scottsdale

92093

RECRUITING

University of California, San Diego, La Jolla

06520

RECRUITING

Yale University, New Haven

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Mayo Clinic

OTHER

collaborator

Yale University

OTHER

collaborator

University of Arizona

OTHER

collaborator

Harvard University

OTHER

collaborator

Brigham and Women's Hospital

OTHER

collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

University of California, San Diego

OTHER

NCT06385236 - Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping | Biotech Hunter | Biotech Hunter