Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients

RecruitingOBSERVATIONAL
Enrollment

250

Participants

Timeline

Start Date

January 29, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2026

Conditions
Staphylococcus Aureus ColonizationSurgical Site InfectionsHealthcare Associated Infections
Interventions
OTHER

Screening and decolonization for SA carriers with the 3 drug bundle

nasal mupirocin, chlorhexidine gluconate (CHG) mouth rinse and CHG soap showers x 5 days and non-SA carriers receive 2 CHG pre-op showers

OTHER

No screening for SA

All receive the 3 drug bundle, Nasal mupirocin, chlorhexidine gluconate (CHG) mouth rinse, and CHG body wash

OTHER

no screening

giving pre-surgical patients the three drug decolonization bundle without screening

OTHER

Nasal povidone-iodine on surgery day plus 2 CHG pre-op showers without screening.

Nasal povidone-iodine on surgery day plus 2 CHG pre-op showers without screening.

OTHER

Nasal alcohol gel on surgery day plus 2 CHG pre-op showers without screening

Nasal alcohol gel on surgery day plus 2 CHG pre-op showers without screening

Trial Locations (1)

55414

RECRUITING

University of Minnesota Medical Center and Clinics, Minneapolis

All Listed Sponsors
lead

University of Minnesota

OTHER