Non-surgical Treatment of Chronic Periodontitis With an Adjunctive Vitamin E and Coenzyme Q10 Supplementation

NAEnrolling by invitationINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

March 20, 2024

Primary Completion Date

May 20, 2024

Study Completion Date

November 15, 2024

Conditions
Periodontal Diseases
Interventions
DRUG

Receive 30 mg of Coq10

A total of 120 individuals diagnosed with chronic periodontitis were selected for this study. These participants were randomly assigned to two different groups. The purpose of the study was to measure the periodontal parameters of the two molars adjacent to the mandible using a periodontal probe. All of the patients received scaling and root planing (SRP) as part of their treatment. However, the treatment groups differed in terms of the supplements they received. Group A was given a daily dose of Coq10 at 30 mg, while Group B received a daily dose of Vitamin E at 400 mg; Furthermore, group C did not receive any supplements. The periodontal examination involved a total of 300 teeth across the three groups. In addition to this, 2 ml of unstimulated saliva was collected from each patient both before and after 2 months. The purpose of collecting the saliva samples was to evaluate the total antioxidant capacity and determine if there were any changes over time.

Trial Locations (1)

1947833113

Amirhossein Farahmand, Tehran

All Listed Sponsors
lead

Islamic Azad University, Sanandaj

OTHER