NCT06372899View on ClinicalTrials.gov

Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers

NARecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

October 2, 2024

Primary Completion Date

November 30, 2027

Study Completion Date

March 31, 2028

Conditions
E-cigarette UseCigarette SmokingHarm ReductionTobacco Use
Interventions
OTHER

E-cigarettes

Participants randomized to ECIGS are instructed to switch from smoking combustible cigarettes to using e-cigarettes for 6 weeks. They will be provided with an e-cigarette device and nicotine pods.

OTHER

Oral nicotine pouches

Participants randomized to ONPS are instructed to switch from smoking combustible cigarettes to using nicotine pouches for 6 weeks. They will be provided with nicotine pouches.

Trial Locations (1)

19104

RECRUITING

University of Pennsylvania, Philadelphia

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

University of Pennsylvania

OTHER

lead

Abramson Cancer Center at Penn Medicine

OTHER