Newly Emerging Immunotherapy for Pancreatic Cancer Treatment

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

117

Participants

Timeline

Start Date

April 30, 2024

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2027

Conditions
Pancreatic Cancer
Interventions
DRUG

JS001

240 mg by IV infusionevery 3 weeks (Q3W), given on cycle day 1.

DRUG

JS004

200 mg by IV infusion Q3W, given on cycle day 1.

DRUG

JS007

3mg/kg by IV infusion Q3W, given on cycle day 1.

DRUG

JS015

600mg by IV infusion Q3W, given on cycle day 1.

DRUG

Irinotecan Liposome Injection

60 or 70 mg/m\^2 by IV infusion every 2 weeks (Q2W), given on cycle day 1.

DRUG

5-Fluorouracil (5-FU)

2400mg/m\^2, intravenously, over 46 h on day 1, Q2W.

DRUG

Leucovorin (LV)

400mg/m\^2, intravenously, over 30 min on day 1, Q2W.

DRUG

Nab paclitaxel

125 mg/m\^2 by IV infusion Q3W, given on cycle day 1 and 8.

DRUG

Gemcitabine

1000 mg/m\^2 by IV infusion Q3W, given on cycle day 1 and 8.

Trial Locations (1)

200032

Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center; Pancreatic Cancer Institute, Fudan University, Shanghai

All Listed Sponsors
lead

Fudan University

OTHER

NCT06370754 - Newly Emerging Immunotherapy for Pancreatic Cancer Treatment | Biotech Hunter | Biotech Hunter