40
Participants
Start Date
February 29, 2024
Primary Completion Date
March 4, 2025
Study Completion Date
December 31, 2025
Mupirocin (50 mg)
50 mg de mupirocin
Mupirocin (500 mg)
500 mg de mupirocin
blood samples after Single dose part
3 blood samples will be performed sampling time ater application of mupirocin (single dose part): 00h30, 1h00, 02h00
nasal swab after Single dose part
7 nasal swab for the detection of S. aureus (type Swab) will be performed after application of mupirocin (single dose part): 00h00, 1h00, 02h00, 04h00, 06h00, 08h00, 12h00
Collection of urine after Single dose part
Collection of urine during 12 hours after the application of mupirocin (Single dose part)
nasal swab during Repeated dose part
5 nasal swab for the detection of S. aureus (type Swab) will be performed during administration of mupirocin (Repeated dose part): 2, 3, 4, 5 et 6 days after the first application of mupirocin (Repeated dose part)
Collection of urine during Repeated dose part
5 collections of urine during Repeated dose part: 2, 3, 4, 5 et 6 days after the first application of mupirocin (Repeated dose part)
nasal swab after Repeated dose part
2 nasal swab for the detection of S. aureus (type Swab) will be performed: 1, 3 months after the first application of mupirocin (Repeated dose part)
CHU de SAINT-ETIENNE, Saint-Etienne
Centre Hospitalier Universitaire de Saint Etienne
OTHER