A Study of Treatment-free Remission in Chronic Phase Chronic Myeloid Leukemia

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

69

Participants

Timeline

Start Date

September 1, 2024

Primary Completion Date

August 31, 2028

Study Completion Date

August 31, 2028

Conditions
Chronic Myeloid Leukemia, Chronic Phase
Interventions
DRUG

Asciminib

that patients who lost MR3.0 after stopping TKIs, thus failed to maintain treatment-free remission can achieve second sustainable MR4.5 by sustainable MR4.5 for more than 3 years once regained and prolong MRFS by adding asciminib to TKIs. Patients will be restarted on TKIs when they fail sustaining MR3.0 after cessation because restarting TKIs when loss of MR3.0 is reasonable in this situation

All Listed Sponsors
lead

Korean Society of Hematology

NETWORK

NCT06368414 - A Study of Treatment-free Remission in Chronic Phase Chronic Myeloid Leukemia | Biotech Hunter | Biotech Hunter