oPen Versus RobotIc retrOmuscular Repair in Medium to Large Ventral Hernias

NANot yet recruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2031

Conditions
Ventral HerniaIncisional HerniaAbdominal Wall Defect
Interventions
PROCEDURE

Robotically-assisted ventral hernia repair (RVHR)

"3 8mm robotic trocars are placed intraabdominally and the DaVinci Xi-robotic system is docked. Adhesiolysis from any adherent structures to the abdominal wall is performed. Incision of the lateral verge of the retromuscular space and retromuscular dissection. Superior and inferior cross-over to the contralateral retromuscular space and dissection of the hernia sac.~Unilateral or bilateral transversus abdominis release (TAR) is performed, if necessary. Running suture with absorbable barbed suture of the posterior rectus sheath and peritoneum, as appropriate. Synthetic retromuscular mesh placement with a mesh-size as large as the prepared surface allows. Closure of the anterior rectus sheath with absorbable barbed running suture. Port extraction, skin closure. Dressing from xyphoid to pubis and 6 lateral dressings for blinding purposes."

PROCEDURE

Open ventral hernia repair (OVHR)

Median laparotomy with a minimal length of the previous scar (in case of incisional hernia) and adhesiolysis is performed, where necessary, to liberate the abdominal wall and the ventral hernia from adhesions. Bilateral dissection of the posterior rectus sheath under visualisation and sparing of the epigastric vessels and neurovascular bundles. Closure of the posterior rectus sheath with a slowly-absorbable running suture. Indication for a uni- or bilateral TAR identical to the intervention group. Retromuscular synthetic mesh placement with a mesh-size as far as the prepared surface allows. Mesh fixation optional with either absorbable sutures to the posterior sheath or with glubran glue. Closure of the anterior rectus sheath with a slowly-absorbable running suture. Skin closure. Dressing from xyphoid to pubis and 6 lateral dressings for blinding purposes.

All Listed Sponsors
collaborator

St. Clara Hospital, Basel, Switzerland

UNKNOWN

collaborator

Klinikum Kempten, Kempten, Germany

UNKNOWN

lead

University Hospital, Basel, Switzerland

OTHER

NCT06364306 - oPen Versus RobotIc retrOmuscular Repair in Medium to Large Ventral Hernias | Biotech Hunter | Biotech Hunter