32
Participants
Start Date
July 28, 2025
Primary Completion Date
December 31, 2026
Study Completion Date
December 31, 2026
Placebo
Placebo intranasal spray liquid with no oxytocin will be delivered in 2 puffs to each nostril daily for 21 days. The first single dose will be administered at the clinic (Visit 1).
Oxytocin Intranasal Spray 12 International Unit (12IU)
Participants weighing less than 40 kg (88 pounds) will receive 12 IU of oxytocin delivered as 1 puff (6 IU) to each nostril daily for 21 days. The first single dose will be administered at the clinic (Visit 1).
Oxytocin Intranasal Spray 24 International Unit (24IU)
Participants weighing more than 40 kg (880 pounds) will receive 24 IU of oxytocin delivered as 2 puffs (12 IU) to each nostril daily for 21 days. The first single dose will be administered at the clinic (Visit 1).
Functional MRI
Functional MRI (fMRI) scan with affective Stroop and Empathy and Theory of Mind task (EmpaTom task will administered pre- and post-administration of oxytocin.
RECRUITING
University of Nebraska Medical Center, Department of Psychiatry, Omaha
University of Nebraska
OTHER